RegFormer: a single-cell foundation model powered by gene regulatory hierarchies
这篇工作的关键不只是又做了一个 single-cell foundation model，而是把 gene regulatory hierarchies 明确接进了 foundation-model 接口。它瞄准的是现有单细胞模型常见的两个短板：缺 regulatory awareness，以及难以同时兼顾规模...
SCMBench: benchmarking domain-specific and foundation models for single-cell multi-omics data integration
single-cell multi-omics integration 这条线已经不缺模型，但一直缺一套能把 domain-specific models 和 foundation models 放到同一张可操作坐标系里的评测接口。SCMBench 的贡献就在这里：它不是只比 integration accur...
Advancing regulatory variant effect prediction with AlphaGenome
- 分级：`颠覆性` - 正式标题：`Advancing regulatory variant effect prediction with AlphaGenome` - 原文：`2026-01-28-LS1_AlphaGenome-Advancing_regulatory_variant_effect_pre...