收录解读
这篇 Nature Neuroscience 论文研究人类前额叶如何把依赖任务上下文的行动信息传递给运动皮层。
作者使用人类直接脑记录,发现跨区群体活动并非全维度广播,而是通过特定 communication subspace 高效中继行动信息。
这与本库此前收录的 hippocampal-retrosplenial subspace communication 形成互补:不同认知任务可能都依赖低维子空间完成跨区信息路由。
它值得收录,因为 communication subspace 是 NeuroAI 中非常重要的可迁移抽象,可启发模块化 agent、动作条件路由、上下文门控和低维控制接口。
原始摘要与中文对照
中文对照翻译
适应性行为依赖于将抽象规则和目标转化为适合当前情境的行动的能力。前额叶皮层 (PFC) 中的神经群体活动被认为通过高维动态支持这种灵活的计算,而初级运动皮层 (M1) 中的活动则更直接地与运动执行相关。PFC 中的情境表征如何转化为 M1 中随后的行动计划仍然未知。先前的工作表明,低维编码子空间可能组织区域间通信,但在人类中缺乏这种群体层面通信机制的直接证据。在这里,我们使用来自人PFC和M1的颅内记录来识别一个嵌入在高维PFC活动中的通信子空间,该子空间在单次试验层面选择性地传递行为相关信息。这个子空间中的活动比任一区域都更强地预测情境依赖性行动,揭示了一个基本编码原理,即协调的区域间群体动态通过它过滤并传递预测信息,以指导情境依赖性行动。
原始摘要
Adaptive behavior relies on the ability to translate abstract rules and goals into actions suited to the current context. Neural population activity in the prefrontal cortex (PFC) has been proposed to support such flexible computations through high-dimensional dynamics, whereas activity in the primary motor cortex (M1) is related more directly to movement execution. How contextual representations in PFC are transformed into ensuing action plans within M1 remains unknown. Previous work suggests that low-dimensional coding subspaces might organize interareal communication, but direct evidence for such population-level communication mechanisms in humans is lacking. Here we use intracranial recordings from human PFC and M1 to identify a communication subspace embedded within high-dimensional PFC activity, that selectively relays behaviorally relevant information at the single-trial level. Activity in this subspace predicts context-dependent action more strongly than either region, revealing a fundamental coding principle by which coordinated interareal population dynamics filter and relay predictive information to guide context-dependent actions.